EXPRESSION OF FRS2 IN ATYPICAL LIPOMATOUS TUMOR/WELL-DIFFERENTIATED LIPOSARCOMA AND DEDIFFERENTIATED LIPOSARCOMA: AN IMMUNOHISTOCHEMICAL ANALYSIS OF 182 CASES WITH GENETIC DATA

Abstract Background The fibroblast growth factor receptor substrate 2 (FRS2) gene is located close to MDM2 and CDK4 within the 12q13-15 chromosomal region.FRS2 gene was recently found to be consistently amplified in atypical lipomatous tumor (ALT)/well-differentiated liposarcoma (WDL) and dedifferentiated liposarcoma (DDL), suggesting the detection

We report a 60-year-old woman who presented to the emergency department after experiencing a witnessed unknown onset bilateral tonic clonic seizure (GTCS) that culminated in cardiac arrest.A neurology consultant uncovered a years-long history of frequent episodic staring followed by confusion and expressive aphasia, which strongly suggested that sh

The article is devoted to the definition of narrative perspective as synthesis of subject-speech, composite-thematic and spatial-temporal plans of the narrative literary text conditioned by the corresponding communicative and creative strategy, or conceptual and thematic positions of the author.The typology of narrative forms given in this article

This paper focuses on the reinforcement effect of full-face anchorage in thick soft rock roadway.A 2D semimodel of full-face anchorage in roadway with thick surrounding soft rock was proposed firstly by transforming the confinement effect of the excavation face in the longitudinal direction as the virtual internal support force at the circumferenti

Very few experimental studies of full pinion engagement planetary gear trains have been published; therefore, their behavior under load is little known.In this paper, the results from the experimental studies of the above-mentioned gear trains are presented, whereby the bending stresses in the planet pins are displayed both in time and frequency do